Regional Centre of NMR spectroscopy

The High field NMR Regional Centre was founded by the Department of Chemistry of the Université de Montréal.

Its purpose is to provide access to high field NMR equipments for academic, governmental and industrial researchers, mostly from Quebec. This cutting edge equipment is expensive and often unavailable in many research institutions.

Ours goals are:

To provide high field NMR spectra for research groups or industries not specialized in NMR.
To offer the possibility for researchers specialized in the field of NMR to undertake more fundamental studies.

Useful documents for internal users

UdeM DEPARTMENT OF CHEMISTRY USERS ONLY

Use this link to make your training request
Complete this form for your analysis requests and attach it to your sample

Rates and procedure

For EXTERNAL USERS ( Other department, other university, industry, etc.)

The Regional Centre of NMR spectroscopy uses the rates as below, according to the source of the request.

Rates

Fill out the analysis request form and sent it to the Centre by e-mail or fax (514 343-7586). Then, send the samples to the Department of Chemistry :

To send samples by Canada Post

High Field NMR Laboratory - A/s Pedro Aguiar
Université de Montréal
Department of Chemistry
PO Box 6128 Centre-ville STN
Montréal QC H3C 3J7

To send samples by private services

High Field NMR Laboratory - a/s Pedro Aguiar (B-3343)
Université de Montréal
Department of Chemistry
1375 Ave. Thérèse LAvoie Roux
Quai de réception #2
Outremont QC H2V 0B3

Instruments

Regional Centre of NMR spectroscopy is equipped with 7 spectrometers: 5 for the liquid phase and 2 for the solid phase.

NMR liquid instruments

Bruker AVANCE II 700

Bruker AV700 spectrometer is located in Room B-0161 of the Science Complex, MIL Campus. The spectrometer hardware is described as follow:

16.4 Tesla actively shielded magnet (2006)
3 channel console allowing triple resonance experiments (2006)
5 mm cryoprobe for ¹H and ¹³C.
24 tubes autosampler.

With this probe, the signal/noise ratio is approximately 1800 for ¹³C and 3200 for ¹H. This configuration allows users to easily obtain 1H and 13C spectra. Furthermore, all 2D experiments such as COSY, TOCSY, NOESY, ROESY, HSQC and HMBC on a very small amount of product are possible. To optimize the concentration of the solution, tubes with different diameters can be used such as 1.7 mm, 2 mm, 2.5 mm, 3mm and 5 mm tubes. Using selective excitation, 1D versions of the preceding experiments are also available. Solvent suppression experiments are also very effective.

Other probes available for this instrument:

a. 5 mm TXI probe allowing observation of ¹H, ¹³C and ¹⁵N for all triple resonance experiment and all multidimensional experiments.

As of today, this instrument is operated by the NMR staff who will work in collaboration with researchers to optimize performances and get the best results possible with the spectrometer. To submit a sample for analysis, please fill in the analysis request form and call 514 343-5857 to schedule a meeting.

Bruker AVANCE III 400

Bruker AVIII 400 spectrometer is located in Room B-0161 of the Science Complex, MIL Campus.

The spectrometer hardware is described as follow:

9.4 Tesla magnet (2012)
3 channel console (2012)
5 mm Prodigy cryoprobe allowing observation of ¹H, ¹⁹F and all frequencies between ¹⁵N and ³¹P with automatic tuning and matching.

With this probe, the signal/noise ratio is approximately 500 for ¹³C and 1100 for ¹H. This configuration allows users to easily obtain spectra for a wide range of nuclei frequencies between ¹⁵N and ³¹P, with ¹H decoupling. ¹⁹F NMR is also possible. Furthermore, all 2D experiments such as COSY, TOCSY, NOESY, ROESY, HSQC and HMBC on a very small amount of product are possible.

To optimize the concentration of the solution, tubes with different diameters can be used such as 3 mm and 5 mm tubes. Using selective excitation, 1D versions of the preceding experiments are also available. Solvent suppression experiments are also very effective.

Other probe available for this instrument:

a. 5 mm BBO probe allowing observation of ¹H and all frequencies between ¹⁵N and ³¹P with automatic tuning and matching.

Bruker AV500

Bruker AV500 spectrometer is located in Room B-3316 of the Science Complex, MIL Campus. This spectrometer is accessible by all research groups from the Department of Chemistry. The spectrometer hardware is described as follow:

11.74 Tesla actively shielded magnet (2005)
3 channel console allowing triple resonance experiments (2005)
5 mm BBFO probe allowing observation of ¹H, ¹⁹F and all frequencies between ¹⁵N and ³¹P with automatic tuning and matching.
60 tubes autosampler

This configuration allows users to easily obtain spectra for a wide range of nuclei frequencies between ¹⁵N and ³¹P, with ¹H decoupling. ¹⁹F NMR is also possible. Furthermore, all 1D or 2D experiments based on 1H/X pairs such as DEPT, COSY, TOCSY, NOESY, ROESY, HSQC and HMBC are possible. Using selective excitation, 1D versions of the preceding experiments are also available.

Other probes available for this instrument:

5 mm TBI probe with ¹H, ¹³C and ¹⁰⁹ag-³¹P channels. Optimized for inverse experiments, all 2D experiments like COSY, TOCSY, NOESY, ROESY, HSQC and HMBC give better results. This probe is also optimized for solvent suppression experiments.
5 mm BBO probe for ¹H and all nuclei frequencies between ¹⁵N and ³¹P observation with automatic tuning and matching
4 mm HRMAS probe with ¹H, ¹³C and ³¹P channels

Bruker AVANCE II 400

Bruker AVII 400 spectrometer is located in Room B-3316 of the Science Complex, MIL Campus. This spectrometer is accessible by all research groups from Department of the Chemistry. The spectrometer hardware is described as follow:

9.4 Tesla magnet (2005)
2 channel console (2005)
5 mm BBFO probe allowing observation of ¹H, ¹⁹F and all frequencies between ¹⁵N and ³¹P with automatic tuning and matching.
60 tubes autosampler

This configuration enables users to easily obtain spectra for a wide range of nuclei frequencies between ¹⁵N and ³¹P, with ¹H decoupling. ¹⁹F NMR is also possible. Furthermore, all 1D or 2D experiments based on ¹H/X pairs such as DEPT, COSY, TOCSY, NOESY, ROESY, HSQC and HMBC are possible. Using selective excitation, 1D versions of the preceding experiments are also available.

Other probes available for this instrument:

5 mm BBO probe for 1H and all nuclei frequencies between ¹⁵N and ³¹P observation, with automatic tuning and matching.
5 mm TXO probe with ¹H, ¹³C and ¹⁹F channels. Optimized for ¹³C {¹H and ¹⁹F}, the probe also enables all 1D or 2D experiments implying those 3 nuclei.
5 mm BBI probe for observation of ¹H and decoupling of all frequencies between ¹⁰⁹Ag and ³¹P. Optimized for inverse experiments, all 2D experiments like COSY, TOCSY, NOESY, ROESY, HSQC and HMBC give better results. This probe is also optimized for solvent suppression experiments.

Bruker Avance NEO 400

Bruker AVNEO400 spectrometer is located in Room B-3316 of the Science Complex, MIL Campus. This spectrometer is accessible by all research groups from the Department of Chemistry. The spectrometer hardware is described as follow:

9.4 Tesla actively shielded magnet (2000)
2 channel console enabling double resonance experiments (2022)
5 mm BBFO probe allowing observation of ¹H, ¹⁹F and all frequencies between ¹⁵N and ³¹P with automatic tuning and matching.

Other probes available for this instrument:

5 mm BBO probe for ¹H and all nuclei frequencies between ¹⁵N and ³¹P observation, with automatic tuning and matching.
5 mm BBI probe for observation of ¹H and decoupling of all frequencies between ¹⁰⁹Ag and ³¹P. Optimized for inverse experiments, all 2D experiments like COSY, TOCSY, NOESY, ROESY, HSQC and HMBC give better results. This probe is also optimized for solvent suppression experiments.

NMR solid instruments

Bruker AVANCE 600 WB

Bruker Avance 600 WB spectrometer is located in Room B-0161 of the Science Complex, MIL Campus. The spectrometer hardware is described as follow:

Wide bore (89mm) 14.1 Tesla actively shielded magnet (2003)
3 channel console (2003)
Diffusion and micro-imaging system:

3 channels electronically controlled gradient system
60A linear amplifier
Two 40A linear amplifiers
Gradient coils chiller

Probes available:

1.3 to 7 mm CP/MAS double or triple resonance probe, allowing sample rotation up to 65 KHz
5 mm large band (WL) probe, single and double resonance
5 mm to 10 mm Large band (WL) probe, single and double resonance
2.5 mm to 30 mm micro-imaging single and double resonance probe with 2.5 or 5 G/cm/A gradients
5 mm and 8 mm diffusion single and double resonance probe with 30 or 60 G/cm/A gradients
7 mm LAS-MAS High-temperature (800 C) probe

This advanced research dedicated instrument allows the most up to date and advanced solid NMR experiments and diffusion/imaging (proton solid state NMR, protein structure in solid state, MQMAS, etc.). As of today, this instrument is operated by the NMR staff who will work in collaboration with researchers to optimize performances and get the best results possible with the spectrometer.

To submit a sample for analysis, please fill in the analysis request form and call 514 343-6111, ext. 1966 to schedule a meeting.

Bruker AVANCE II 400 WB

Bruker Avance II 400 WB spectrometer is located in Room B-3316 of the Science Complex, MIL Campus. The spectrometer hardware is described as follow:

Wide bore (89 mm) 9.4 Tesla actively shielded magnet (2005)
2 channel console (2005)
Diffusion and micro-imaging system:

Gradient system: 3 channels
60A linear amplifier
Two 40A linear amplifer
Gradient coil chiller

Other probes available for this instrument:

4 mm CP/MAS gradient double resonance 1H/15N-31P probe, allowing sample rotation up to 15 KHz

5 mm to 10 mm Large band (WL) probe, single and double resonance.

5 mm to 30 mm micro-imaging single and double resonance probe with 2.5 or 5 G/cm/A gradients

5 mm to 10 mm diffusion single and double resonance probe with 30 or 60 G/cm/A gradients

Although this instrument is mainly used for diffusion and micro-imaging, it is possible upon user request to modify it for their needs. To submit a sample for analysis, please fill in the analysis request form and call 514 343-6111, ext. 1966 to schedule a meeting.